Jiří Šponer教授致力于DNA/RNA结构、核酸与蛋白或配体相互作用的多尺度理论和计算研究,特别是非经典的DNA/RNA二级结构(例如G4,i-motif等)。相关研究成果详见Šponer教授网站:https://www.ibp.cz/en/research/d … lications-full-list。
本次招聘是基于MARIE-SKŁODOWSKA-CURIE EUROPEAN TRAINING NETWORK项目,待遇相当可以, 欢迎大家积极报名哟。
项目具体介绍、要求以及待遇如下:
The Director of Central European Institute of Technology (CEITEC MU) opens a position in MARIE-SKŁODOWSKA-CURIE EUROPEAN TRAINING NETWORK LightDyNAmics
EARLY STAGE RESEARCHER ADVANCED COMPUTIONAL STUDIES OF STRUCTURAL DYNAMICS OF DNA AND RNA SYSTEMS
【Description】
CEITEC is a scientific institute in the fields of life sciences,
advanced materials and technologies whose aim is to establish itself as a
recognized centre for basic as well as applied research. CEITEC offers a
state-of-the-art infrastructure and great conditions to employ
excellent researchers.
Our institute values diversity and promotes an inclusive working environment with the aim to support the best scientists.
An Early Stage Researcher position is available in Jiří Šponer lab (http://www.ibp.cz/en/departments/structure-and-dynamics-of-nucleic-acids/info-about-the-department//;
CEITEC, Masaryk University, Brno, Czech Republic) to participate in
research focused on Multiscale theoretical and computational studies
(using explicit-solvent atomistic molecular dynamics simulation methods
and quantum chemistry) of DNA and RNA molecules, and their molecular
interactions with proteins and ligands, with a specific emphasis given
to non-canonical molecules such as guanine quadruplexes or folded RNA
molecules. The research can be focused on applications as well as method
development, in the latter case with emphasis given to development and
testing of the simulation force fields.
【Requirements】
1.
Successful candidate must hold the equivalent of a Czech Master’s
degree (Mgr., Ing., MSc.) from an institution of recognized standing
(four or five year undergraduate degree), must have no more than 4 years
of full-time research experience, and must not have been awarded a
doctoral degree at the time of recruitment.
2. Prior experience in
computational studies of nucleic acids (preferable) or proteins,
including a relevant research publication in the field, is requested.
3. Spent at least 2 whole years out of the last 3 outside the Czech Republic.
4. Good English language – spoken and written.
【We offer】:
1、Enrolment in CEITEC PhD School (detailed information available at: http://ls-phd.ceitec.cz/) and a diverse training programme of the LightDyNAmics Marie Skłodowska-Curie European Training Network (MSCA-ETN).
2、Interesting position in a dynamically expanding research institute.
3、An
attractive salary and benefits package within the MSCA-ETN
LightDyNAmics (2300 EUR gross salary plus 370 EUR family contribution if
applicable). Current average gross salary in the Czech Republic is
28700 CZK (1130 EUR), minimum salary is 12.200 CZK (480 EUR).
4、Background of a recognized and successful institution with supportive and international working environment.
5、Environment promoting interdisciplinarity and intersectorality of research.
6、Excellent in house computational facilities and direct collaboration with experimental laboratories.
7、Experienced research team covering a broad range of topics and computational methodologies.
8、Involvement in prestigious international ITN research training network.
9、Support with the relocation process (welcome office service).
10、6 weeks of paid holiday.
【About LighDyNAmics Marie-Skłodowska-Curie European Training Network】
【Abstract】:
Light interaction with biomaterials is the driving mechanism of
fundamental biological processes, from photosynthesis to DNA
photodamage, and is a powerful tool in biomedicine for analytical,
diagnostic and therapeutic purposes.
The main goal of
LightDyNAmics is to achieve a complete understanding of the ultrafast
dynamical processes at the molecular scale induced by UV light
absorption in DNA, and to unveil the mechanisms leading to photodamage
of the genetic code. At the same time, our project will transfer this
knowledge on light-matter interaction to a broad class of optoelectronic
materials, highly relevant for Europe`s hightech industries.
LightDyNAmics is an academia-industry research environment training 15
Early Stage Researchers (ESRs) by crossing the traditional border
between theoretical and experimental expertise. This will be achieved by
performing independent, yet interrelated and complementary research
projects focussed on photoactivated dynamics of DNA, and by developing a
variety of new spectroscopic and computational methods. For all the
ESRs, personalised training in advanced techniques will be combined with
a broad common interdisciplinary background on dynamical processes in
bio-macromolecules.
The consortium brings together 10 leading
academic groups with multidisciplinary expertise (chemistry, physics,
biology) and a unique blend of experimental and computational skills. 6
innovative companies, from SMEs specialised in click-chemistry and in
biosensors to a pharma industry, will be fully integrated in the
research and training programme and help promote technological
exploitation of its results.
LightDyNAmics will develop
innovative molecular probes for DNA/protein interaction, paving the way
to new diagnostic tools and new drugs. The understanding of light
interaction with organic molecules will impact on basic sciences, from
biochemistry to nanosciences, and on industrial applications ranging
from healthcare to photonic technologies.
【Partners】:
Consiglio
Nazionale delle Ricerche, Istituto di Biostrutture è Bioimmagini (IT),
Centre National de la Recherche Scientifique, Lasers, Interactions and
Dynamics Laboratory (FR), University of Durham (UK), Kemijski Inštitut
(SI), Ludwig-Maximilians-Universität München (DE), Masarykova Univerzita
(CZ), Politecnico di Milano (IT), University College Dublin (IE),
Università di Bologna (IT), Universität Wien (AT), AstraZeneca Ltd (UK),
Baseclick GmbH (DE), Dynamic Biosensors GmbH (DE)
For further information about:
-CEITEC, please visit www.ceitec.eu
-CEITEC Welcome Office, please visit http://www.ceitec.eu/ceitec-welcome-office/t1137
-Masaryk University, please visit www.muni.cz
-Brno, please visit http://www2.brno.cz/index.php?lan=en&nav01=20608&nav02=20617
项目开始日期:2018年9月
有意申请人请提供个人简历、个人研究总结和已发表论文列表。
申请材料请发至:Olga Křížová的邮箱 phd@ceitec.muni.cz(英文)。
谢谢!